Noda T, Sakurai N, Nozawa K, Kobayashi S, Devlin DJ, Matzuk MM, Ikawa M. Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice. Andrology. 2019 [epub ahead of print]
Tobita T, Kiyozumi D, Muto M, Noda T, Ikawa M. Lvrn expression is not critical for mouse placentation. J Reprod Dev. 2019 [epub ahead of print]
Shimada K, Kato H, Miyata H, Ikawa M. Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis. J Reprod Dev. 2019 [epub ahead of print]
Matsumura T, Endo T, Isotani A, Ogawa M, Ikawa M. An Azoospermic Factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility. J Reprod Dev. 2019 Jan 7. [epub ahead of print]
Noda T, Fujihara Y, Matsumura T, Oura S, Kobayashi S, Ikawa M. Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity.Biol Reprod. 2018 Nov 18.
Fujihara Y, Oji A, Kojima-Kita K, Larasati T, Ikawa M. Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice.J Cell Sci. 2018 Oct 8;131(19).
Abbasi F, Miyata H, Shimada K, Morohoshi A, Nozawa K, Matsumura T, Xu Z, Pratiwi P, Ikawa M. RSPH6A is required for sperm flagellum formation and male fertility in mice.J Cell Sci. 2018 Oct 11;131(19).
Oura S, Miyata H, Noda T, Shimada K, Matsumura T, Morohoshi A, Isotani A, Ikawa M. Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice. Exp Anim. 2018 Aug 9.
Nozawa K, Satouh Y, Fujimoto T, Oji A, Ikawa M. Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice. Sci Rep. 2018 Jan 22;8(1):1315.
Sasanuma S, Ozawa M, Yoshida N. The RNA binding protein Ptbp1 is essential for BCR-mediated antibody production. Int Immunol (accepted)
Senoo M, Takijiri T, Yoshida N, Ozawa M, Ikawa M.PTBP1 contributes to spermatogenesis through regulation of proliferation in spermatogonia. J Reprod Dev (accepted)
Fujihara Y, Oji A, Larasati T, Kojima-Kita K, Ikawa M
Human globozoospermia-related gene Spata16 is required for spermformation revealed by CRISPR/Cas9-mediated mouse models.
International Journal of Molecular Sciences, 18(10): 2208 (2017)
Castaneda JM, Hua R, Miyata H, Oji A, Guo Y, Cheng Y, Zhou T, Guo X, Cui Y, Shen B, Wang Z, Hu Z, Zhou Z, Sha J, Prunskaite-Hyyrylainen R, Yu Z, Ramirez-Solis R, Ikawa M, Matzuk MM, Liu M. TCTE1 is a conserved component of the dynein regulatory complex and is required for motilityand metabolism in mouse spermatozoa.Proc Natl Acad Sci U S A. pii: 201621279 (2017)
Tribulo P, Moss JI, Ozawa M, Jiang Z, Tian C, Hansen PJ. WNT regulation of embryonic development likely involves pathways independent of nuclear CTNNB1. Reproduction 153:405-419 (2017)
Zhang X, Chen H, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA. Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell 166:1147-1162 (2016)
Ozawa M, Sakatani M, Dobbs K, Kannampuzha-Francis J, Hansen PJ. Regulation of gene expression in the bovine blastocyst by colony stimulating factor 2. BMC Research Notes 9:250 (2016)
Ozawa M, Fukuda T, Sakamoto R, Honda H, Yoshida N. The Histone Demethylase FBXL10 Regulates the Proliferation of Spermatogonia and Ensures Long-Term Sustainable Spermatogenesis in Mice. Biol Reprod 94:1-11 (2016)
Yang QE, Ozawa M, Zhang K, Johnson S, Ealy AD. The requirement for protein kinase C delta (PRKCD) during preimplantation bovine embryo development. Reprod Fertil Dev 28:482-490 (2016)
Ozawa M, Kawakami E, Sakamoto R, Shibasaki T, Goto A, Yoshida N. Development of FGF2-dependent pluripotent stem cells showing naive state characteristics from murine preimplantation inner cell mass. Stem Cell Res 13:75-87 (2014)
Kawakami E, Tokunaga A, Ozawa M, Sakamoto R, Yoshida N. The histone demethylases Fbxl11 plays an essential role in embryonic development by repressing cell-cycle regulators. Mech Devel 135:31-42 (2014)
Nakai M, Ozawa M, Maedomari N, Noguchi J, Kaneko H, Ito J, Onishi A, Kashiwazaki N, Kikuchi K. Delay in cleavage of porcine embryos after intracytoplasmic sperm injection (ICSI) shows poorer embryonic development. J Reprod Dev 60:256-259 (2014)
Ozawa M, Yang QE, Ealy AD. The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro. Reproduction 145:191-201 (2013)
Sakatani M, Bonilla L, Dobbs KB, Block J, Ozawa M, Shanker S, Yao J, Hansen PJ. Changes in the transcriptome of morula-stage bovine embryos caused by heat shock: relationship to developmental acquisition of thermotolerance. Reprod Biol Endocrinol 11:3 (2013)
Dobbs KB, Khan FA, Sakatani M, Moss JI, Ozawa M, Ealy AD, Hansen PJ. Regulation of pluripotency of inner cell mass and growth and differentiation of trophectoderm of the bovine embryo by colony stimulating factor 2. Biol Reprod 89:1-10 (2013)
Ozawa M, Sakatani M, Yao J, Shanker S, Yu F, Yamashita R, Wakabayashi S, Nakai K, Dobbs KB, Sudano MJ, Farmerie WG, Hansen PJ. Global gene expression of the inner cell mass and trophectoderm of the bovine blastocyst. BMC Dev Biol 12:33 (2012)
Ozawa M, Sakatani M, Hankowski KE, Terada N, Dobbs KB, Hansen PJ. Importance of culture conditions during the morula-to-blastocyst period on capacity of inner cell-mass cells of bovine blastocysts for establishment of self-renewing pluripotent cells. Theriogenology 78:1243-1251 (2012)
Nunomura S, Shimada S, Kametani Y, Yamada Y, Yoshioka M, Suemizu H, Ozawa M, Itoh T, Kono A, Suzuki R, Tani K, Ando K, Yagita H, Ra C, Habu S, Satake M, Sasaki E. Double expression of CD34 and CD117 on bone marrow progenitors is a hallmark of the development of functional mast cell of Callithrix jacchus (common marmoset). Int Immunol 24:593-603 (2012)
Bonilla AQ, Oliveira LJ, Ozawa M, Newsom EM, Lucy MC. Hansen PJ. Developmental changes in thermoprotective actions of insulin-like growth factor-1 on the preimplantation bovine embryo. Mol Cell Endocrinol 332:170-179 (2011)
Bonilla AQ, Ozawa M, Hansen PJ. Timing and dependence upon mitogen-activated protein kinase signaling for pro-developmental actions of insulin-like growth factor 1 on the preimplantation bovine embryo. Growth Horm IGF Res 2:107-111 (2011)
Ozawa M, Hansen PJ. A novel method for purification of inner cell mass and trophectoderm cells from blastocysts using magnetic activated cell sorting. Fertil Steril 95:799-802 (2011)
Thompson IM, Ozawa M, Bubolz JW, Yang Q, Dahl GE. Bovine luteal prolactin receptor expression: potential involvement in regulation of progesterone during the estrous cycle and pregnancy. J Anim Sci 89:1338-1346 (2011)
Yang QE, Fields SD, Zhang K, Ozawa M, Johnson SE, Ealy AD. Fibroblast Growth Factor 2 Promotes Primitive Endoderm Development in Bovine Blastocyst Outgrowths. Biol Reprod 85:946-953 (2011)
Dang-Nguyen TQ, Kikuchi K, Somfai, Ozawa M, Nakai M, Maedomari Viet-Linh N, Kanai Y, Nguyen BX, Nagai T. Evaluation of developmental competence of in vitro-produced porcine embryos based on the timing, pattern and evenness of the first cleavage and the onset of the second cleavage. J Reprod Dev 56:593-600 (2010)
Maedomari N, Kikuchi K, Nagai T, Fahrudin M, Kaneko H, Noguchi J, Nakai M, Ozawa M, Somfai T, Nguyen LV, Ito J, Kashiwazaki N. Nuclear Replacement of In Vitro-Matured Porcine Oocytes by a Serial Centrifugation and Fusion Method. Reprod Domest Anim 45:659-665 (2010)
Nakai M, Kaneko H, Somfai T, Maedomari N, Ozawa M, Noguchi J, Ito J, Kashiwazaki N, Kikuchi K. Production of viable piglets for the first time using sperm derived from ectopic testicular xenografts. Reproduction 139:331–335 (2010)
Ozawa M, Nagai T, Somfai T, Nakai M, Maedomari N, Miyazaki H, Kaneko H, Noguchi J, Kikuchi K. Cumulus cell-enclosed oocytes acquire a capacity to synthesize GSH by FSH stimulation during in vitro maturation in pigs. J Cell Physiol 222:294-301 (2010)
Somfai T, Noguchi J, Kaneko H, Nakai M, Ozawa M, Kashiwazaki N, Egerszegi I, Rátky J, Nagai T, Kikuchi K. Production of good-quality porcine blastocysts by in vitro fertilization of follicular oocytes vitrified at the germinal vesicle stage. Theriogenology 73:147-156 (2010)